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Fz7-21 TFA (2247635-23-8 free base)
CAS No. ——
Fz7-21 TFA (2247635-23-8 free base)( (Ac)-LPSDDLEFWCHVMY-NH2 TFA )
Catalog No. M29961 CAS No. ——
Fz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameFz7-21 TFA (2247635-23-8 free base)
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NoteResearch use only, not for human use.
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Brief DescriptionFz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively.
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DescriptionFz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively.
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In Vitro——
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In Vivo——
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Synonyms(Ac)-LPSDDLEFWCHVMY-NH2 TFA
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PathwayOthers
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TargetOther Targets
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RecptorEC50: 58 nM (human FZD7 CRD), 34 nM (mouse FZD7 CRD)
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight1910.07
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Molecular FormulaC85H115N18F3O25S2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:(Ac)-{Leu}{Pro}{Ser}{Asp}{Asp}{Leu}{Glu}{Phe}{Trp}{Cys}{His}{Val}{Met}{Tyr}-NH2
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Nile AH, et al. Publisher Correction: A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat Chem Biol. 2018 Sep;14(9):902.
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